The privately-owned airline's flight will serve Jakarta, capital of neighboring Indonesia, an Jayapura in Papua three times a week, the Jakarta Post reported.
Of the 150 seats in the plane, 138 will be economy class and the other 12 business class, a spokesman said.
Efata Papua, controlled by several Papuan businessmen, is one of a dozen new carriers that have sprung up since Indonesia's airline sector was deregulated four years ago.
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